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In the causal process, the product of the a path quantifies the effect of independent variables (l-carnitine, betaine or DMG) on the mediator (TMAO), and the product of the b path quantifies the effect of the mediator (TMAO) on the dependent variable (NAFLD), controlling for independent variables (Reference Sobel19)

However, preliminary studies in non-diabetic obese individuals showed that simultaneous activation of GLP-1 and GIP receptors did not potentiate GLP-1-mediated effects in lowering food intake and appetite (79)

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Tomar con 200 ml de agua junto a una de las principales comidas