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The addition of rotenone alone showed moderate growth inhibition effects on drug resistant (CHO R C5) cells, and a lesser effect on drug sensitive (AuxB1) cells

Individuals with obesity should be counselled to accumulate at least 150 minutes a week of moderate aerobic exercise, such as walking, and to engage in resistance training to preserve lean mass

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For tirzepatide at higher maintenance doses, this becomes relevant

"Because this is a registry-based study, we cannot determine exactly why or how these medications affect mood symptoms, but the association was quite strong," coauthor Markku Lhteenvuo, Ph.D., also from the University of Eastern Finland, said in a statement