Twice-weekly protocols (0.51ml every 34 days) are appropriate during active weight loss phases or when treating hepatic steatosis but are not necessary for maintenance
And we have to recognize that whether your body composition changes, just the simple fact that you're doing a training program, a resistance training program, and or adding in some kind of cardiovascular activity, that's everything
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Short-term dose response studies clearly demonstrate that older patients require a lower GH dose to maintain a given serum IGF-I level (35,36), and it has been observed that serum IGF-I increases in individual patients on long-term therapy if the GH dosage remains constant