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Despite having minimal effects on body weight, treatment with -MSTN/-ActA alone also showed beneficial shifts in the lean/fat body composition in obese mice as previously shown in non-obese mice, NHPs, and humans (Fig

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For the chemogenetic experiments in the PVN, AAV-DIO-hM4Di-EGFP or AAV-DIO-hM3Dq-mCherry was delivered into the PVN of VgluT2-Cre mice

Yes, most lab work is completed directly at our Southwest Sacramento clinic, allowing for faster results and a more streamlined experience

TCDD is capable of modulating signaling processes mediated by both estrogen and progesterone, steroid hormones required for the maintenance of normal uterine physiology