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doi: 10.4103/0973-7847.194044 254

Jung, J., Eo, E., and Ahn, K

B12 deficiency is far more common than most people realise, and even a mild shortfall can cause significant and debilitating symptoms including persistent fatigue and low energy, brain fog and poor concentration, low mood and irritability, muscle weakness, and tingling or numbness in the hands and feet

The consensus also points out that the median Hcy for adults in China is in the range of 1314 umol/L, exceeding the diagnostic standard by more than 30% ( 2 Source and metabolism of Hcy Hcy is a product of demethylation during the methionine cycle, which is the only source of Hcy

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