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In patients with type 2 diabetes and retinopathy, diabetic retinopathy complications may occur

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Well-characterized mechanism including appetite suppression, glucose-dependent insulin secretion, and gastric emptying delay

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Physiological stimulation (such as, for example, physical activity, environmental enrichment, exposure to various diets or even circadian rhythmicity) may significantly change GFAP levels and morphometric parameters of GFAP-positive cellular profiles