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The paradoxical effects of thiocyanate and of thyrotropin on the organic binding of iodine by the thyroid in the presence of large amounts of iodide

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This chapter explores the top-ranked risks from the survey and highlights how organizations that take a proactive, integrated approach can turn complexity into opportunity

Two estimands (treatment regimen estimand and efficacy estimand), based on the ICH E9(R1) guidance 32 , were used to assess treatment efficacy from different perspectives and accounted for intercurrent events differently

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