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Additionally, levels of gut microbiota metabolic byproducts, such as short-chain fatty acids, are found to be lower in PCOS patients, which can adversely affect insulin sensitivity and further exacerbate the metabolic issues associated with PCOS (28)

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The v3 integrin-binding RGD4C peptide was conjugated to PD0325901, an MEK1/2 inhibitor, via a GGGGG peptide linker, which enhanced the antitumor activity of the drug against glioblastoma 79