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These modifications allow the peptide to function as a controlled agonist capable of activating two related incretin receptor pathways in laboratory models

Because of the way your immune system responds to live attenuated vaccines differently than sub-unit vaccines

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During the 52-week, randomized withdrawal period (week 36 through week 88), study patients who continued on tirzepatide had an additional mean weight loss of 5.5%, or approximately 6kg/13 pounds