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However, current evidence predominantly derives from animal models and in vitro systems, underscoring the need for large-scale, multicenter clinical trials in high-altitude populations to validate drug-microbiome interactions

Biochem J 326:563566 Willekens H, Chamnongpol S, Davey M, Schraudner M, Langebartels C, VanMontagu M, Inze D, VanCamp W (1997) Catalase is a sink for H 2 O 2 and is indispensable for stress defence in C-3 plants

But they do create an environment where additional support may prove valuable

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