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Questi sono i pazienti che hanno partecipato allo studio REDEFINE 1 e nei quali si sono osservate le perdite peso pi consistenti, fino al 22-23% nei soggetti aderenti al protocollo

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Gut microbiota contribute to MASLD development through various mechanisms, including disruption of liver choline metabolism (necessary for VLDL synthesis and liver lipid export) (150), alterations in bile acid synthesis (151, 152), ethanol production (153), and increased lipopolysaccharides (LPS), which results in liver inflammation (154156)

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As the inflammation settles, the midsection continues to take shape, and the final results become more noticeable over the following months