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Mechanistic studies clarify that its reparative effects on diabetic wounds likely occur by inhibiting ferroptosis in vascular endothelial cells and fibroblasts, thereby improving cellular functions [78, 80]

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DPP-4 also exerts non-catalytic functions via interacting with adenosine deaminase (ADA), caveolin-1, fibronectin, and CXCR4 (70, 71)

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