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Next, GS-4997, a specific ASK1 inhibitor, was used to confirm that the expression of SREBF1 and PLIN2 is regulated by ASK1-p38/JNK signalling

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GLP-1 receptor agonists are synthetic peptides that mimic endogenous GLP-1 to enhance insulin secretion, suppress glucagon, and reduce appetite

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Cartilage degeneration was scored using the Yoshimi scale, which ranges from 0, defined as normal cartilage, to 5, defined as complete loss of cartilage

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10.1016/j.ejphar.2009.01.013 Eur J Pharmacol

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