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Research also indicates that the gtp cyclohydrolase 1/Tetrahydrobiopterin/dihydrofolate reductase (GCH1/BH4/DHFR) pathway, particularly DHFR, suppresses ferroptosis by promoting BH4 synthesis

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Similarly, our study found that use of SGLT2is was associated with a lower but insignificant risk of incident NAFLD/NASH events (i.e., aOR [95% CI]: 0.85 [0.631.15])

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