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Safety data from trials In a paper summarizing 6 randomized, double-blind, placebo-controlled human trials, AOD 9604 did not significantly affect IGF-1 levels, did not impair glucose tolerance, and no serious adverse events (SAEs) were attributed to AOD 9604

Nature 438, 932936

Glutathione (GSH) is considered a high turnover dynamic molecule where it can both be readily oxidized to its disulphide form GSSG or also broken down to its constituent amino acids by the action of endogenous enzymes

Each modification protects one end of the peptide from one of those two enzyme classes

It has been shown that reactive oxygen species (ROS) can mediate reactivation of EBV with the activated promoter Rta 17