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While absorption studies traditionally focus on the small intestine, phenolic acid metabolites degraded by colonic microorganisms constitute approximately 40% of the ingested EGCG, underscoring the significant role of colonic metabolism in EGCG bioavailability

But for many researchers, a 17% reduction represents the threshold where metabolic health markers improve substantially, including fasting glucose, HbA1c, triglycerides, and blood pressure

PMID: 7632946 Article Published Date : Aug 15, 1995 Study Type : Human Study [+] Inhaled glutathione improves symptoms in patients with cystic fibrosis

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This is why many people historically preferred NAC