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"Microdosing GLP-1s means starting at significantly lower doses than standard guidelines sometimes as low as 0.05 to 0.1 mg of semaglutide per week, compared to the usual starting dose of 0.25 mg

Treatment persistence was modest overall, with 49.0% of patients remaining on finerenone and 55.5% on spironolactone at 6 months, declining to 33.8% and 28.3% at 12 months, respectively