In each case, a slight change in the drugs target protein prevents binding without abolishing its normal function
J.van BredaS
Besides this, it also switches the production of eumelanin (a dark brown color) to pheomelanin (a yellow-red color), which leads to the lightening of the skin
Sugiyama T, Sadzuka Y, Nagasawa K, Ohnishi N, Yokoyama T, Sonobe T
however, these drugs have been misused Currently available data do not suggest that rhGH treatment should be used to promote longevity Lack of GH action in mouse models is associated with extended longevity, but the mechanism underlying the increased lifespan has yet to be established Given the effects of reduced GH/IGF-1 signalling on lifespan in rodents, decreased GH action might be beneficial for humans, but clinical trials are needed to assess long-term outcome of GH/IGF-1 inhibition This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access $189.00 per year only $15.75 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF
