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Among patients who persisted with their medication one year after their initial prescriptions, the proportion who achieved 10% or more weight reduction was 61% with semaglutide for obesity, 23.1% with semaglutide for type 2 diabetes, 28.6% with liraglutide for obesity, and 12.3% with liraglutide for type 2 diabetes

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These analyses were kept as sensitivity analyses due to the numerous assumptions required to inform changes in clinical parameters on intensification, and to avoid these unduly influencing cost-effectiveness outcomes in the base case analysis

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