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GLP-1 receptor agonists Glucagon-like peptide-1 (GLP-1) receptor agonists are used to improve glycaemic control in people with type 2 diabetes

C57BL/6J DIR-knockout mice were generated in-house at Helmholtz Munich (Supplementary Information 1)

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It may also change how the medication is absorbed, which can make it less effective

During perimenopause, estrogen levels fluctuate dramatically before eventually declining, potentially creating periods of increased vulnerability to inflammatory conditions like costochondritis