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This patient had no dysmorphic features

doi: 10.1038/s41598-023-34825-1 22 BolducJACollinsJALoeserRF

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This was demonstrated by increased levels of 8-hydroxy-2-deoxyguanosine (8OH2dG), a recognized biomarker for DNA oxidative damage, alongside the upregulation of pro-apoptotic genes such as Bax and p53, and a corresponding downregulation of the anti-apoptotic gene B cell lymphoma 2 (Bcl-2)