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Together, providing the innate harmful effect of NOS blocker L-NAME itself, these findings may emphasize the positive significance of NO in protecting retinal neurons (and thereby, harmful effect of NOS-blockers ( Furthermore, it was demonstrated that NO is continuously produced in the retina and essential for maintenance of retinal blood flow ( Thereby, while the specific mechanism remains to be further elucidated, a rapid recovering effect on the events going on in the central retinal artery in L-NAME retrobulbar rats may also be possible