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Department of Medicine, University Medical Centre Mainz, Johannes Gutenberg University, Mainz, Germany, Mainz, Germany Background: Fib-4 was developed as a non-invasive biomarker to predict advanced fibrosis in other liver disease and was consequently adopted in nonalcoholic fatty liver disease (NAFLD) / nonalcoholic steatohepatitis (NASH) by international guidelines

This triggers adaptive immune responses involving melanocyte-specific T-cell infiltration, amplifying melanocyte destruction 115

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This prompted the further examination of DSePA as a lung radiomitigator to prevent radiation-induced pneumonitis (RP)