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Big picture, high levels of homocysteine have been linked to pregnancy loss, preterm delivery, restricted fetal growth, preeclampsia and other cardiovascular complications

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After 4 weeks at therapeutic doses, most users report 50-70% reduction in pain, significantly improved function, and ability to resume modified training or activities

If human trials with the compound show safety and efficacy, NNMT inhibitors like 5-amino-1MQ could serve to prevent and/or slow age-related muscle deterioration in humans, a tantalizing prospect