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These approaches allow single-cell analyses and the visualization of intercellular heterogeneity (Weill et al., 2019), or the availability of specific and validated antibodies ( Alternatives to microscopy techniques to study organellar organization use biochemical fractionation and mass spectrometry (MS) strategies to assess the localization of large fractions of the endogenous proteome with high throughput and sensitivity ( via centrifugation, biochemical fractionation, or affinity enrichment approaches followed by MS analyses (Yates et al., 2005

Specifically, cell viability plummeted to 31% 0.78% following an 8-hour hypoxic exposure