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Writingreview and editing, N.Y., P.W.R.H., M.L., J.S., G.C., J.W

Dermorphin is a striking exception: it carries a D-alanine at position 2, which the frog produces by enzymatically flipping an L-alanine after the peptide is made

Real-world studies A recent review of real-world studies (RWS) by Ahmad et al

The histidine imidazole ring is the central coordination site for the copper ion, which characterizes the complex biologically

In Mecp2-deficient mice, NTS neurons show significantly reduced amplitudes and frequencies of sIPSCs and mIPSCs, indicating impaired synaptic transmission, and decreased eIPSC amplitudes, though the paired-pulse ratio (PPR) remains unchanged, suggesting that postsynaptic mechanisms may contribute to the weakening of GABAergic inhibition