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NDDSs demonstrate numerous benefits over conventional drug formulations, including enhanced targeted delivery and controlled drug release (Williams et al., 2013), improved solubility and bioavailability (Li et al., 2013), reduced toxicity and side effects, as well as the ability to cross physiological barriers such as the bloodbrain barrier (BBB) (Yoo et al., 2010)

[Google Scholar] 91.Enginar H., Avc G., Eryavuz A., Kaya E., Kucukkurt I., Fidan A.F