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Common side effects of GLP-1 receptor agonists are usually dose-dependent and tend to emerge when you start the medication or increase the dosage

Changes in regional body composition over 8 years in a randomized lifestyle trial: The look AHEAD study

Lincoff, MD, Professor of Neurology

Comparative effectiveness of glucagon-like peptide-1 receptor agonists and other second-line glucose-lowering agents for dementia outcomes in type 2 diabetes mellitus: A cohort study

The reasoning behind this restriction ties back to concerns about cardiovascular effects and the potential for tolerance, where the drug becomes less effective over time as the body adapts to elevated norepinephrine levels