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What started as a diabetes medication is now a popular weight loss drug

Who tends to be a good fit Semaglutide is often a reasonable option for adults with obesity or excess weight plus metabolic risk factors, especially when lifestyle efforts alone have not produced durable results

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In the STEP 1 trial, dual-energy X-ray absorptiometry (DXA) substudies showed that semaglutide treatment resulted in a greater proportional decrease in fat mass compared to lean body mass over 68 weeks, though absolute lean mass reductions were observed alongside the predominant fat loss