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Experiments conducted using a polyacrylamide-based microchannel device that allows independent control of substrate stiffness and channel dimensions revealed that optimal migration of triple-negative MDA-MB-231 and SUM159 human breast cancer cells occurs at intermediate stiffness [90]

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The striking finding: 35 of those 36 studies were preclinical animal experiments

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In SURMOUNT trials, tirzepatide delivered up to 21% weight loss in adults without diabetes over 72 weeks