With a 5% concentration of caffeine combined with a highly-purified EGCG, the formulation helps brighten the appearance of dark circles around the eye area, while also reducing the look of puffiness
ABCG2 rs2231142 has been significantly linked in two studies with decreased serum urate lowering response to allopurinol
High concentrations are also found in the male reproductive tract and the brain
Lipoic acid prevented NOX-induced superoxide production in a rat model of cerebral ischemia and limited infarct volume and neurological deficiencies through upregulating the insulin-phosphatidylinositide-3 kinase (PI3K)-protein kinase B (PKB/Akt) signaling pathway (40)
We collected information on the first author, publication year, country, setting, study design, population characteristics, duration of follow-up, outcome variables of interest, and sources of funding