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Average weight loss in clinical trials of semaglutide ranges from 12-15 percent of body weight over 68 weeks

To understand how we are getting these longer-term effects, we need to study these drugs on a longer time scaleand thats exactly what we did. When the hormone GLP-1 finds a pancreatic beta cell, the ensuing chain of signals, proteins, and gene expression changes that lead to insulin secretion is very well documented

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