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For instance, in a randomised, placebo-controlled, double-blind Phase I study of ascending single doses of cotadutide in healthy individuals with overweight, there were dose-dependent improvements in glucose excursions post meal within 24 h and food intake reduction after a single dose of 100 g [82]

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The mechanisms underlying these health associations remain under investigation, with theories including shared genetic factors, hormonal influences, inflammatory processes, and lifestyle factors

Semaglutide (Ozempic or Wegovy) and liraglutide (Saxenda or Victoza) have shown promising results in small studies for improving metabolic markers in PCOS