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This delayed gastric emptying contributes to reduced postprandial glucose excursions and increased feelings of fullness, though this effect may diminish over time with continued use

How long should a Klow cycle last

This result was replicated in a similar but larger investigation ( N = 1,735) comparing all available GLP-1RAs versus non-GLP-1RA antidiabetics, with this antidepressant association possibly correlating with changes in markers of systemic inflammation (that is, high-sensitivity C-reactive protein) 192

Note: These rates are from Phase 2 trials with ~300 participants