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The role of vitamin E in immunity
den Heijer M, Brouwer IA, Bos GMJ, Blom HJ, van der Put NMJ, Spaans AP, Rosendaal FR, Thomas CMG, Haak HL, Wijermans PW, and Gerrits WBJ (1998)
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Unlike somatic cells, which possess a variety of DNA repair pathways to correct oxidative damage, spermatozoa have only one active DNA repair enzyme, 8-oxoguanine DNA glycosylase (OGG1), which is responsible for repairing oxidative base lesions (73, 74)
These pleiotropic effects provide a rationale for exploring their role in multiple organ systems
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