The model of CTR: rAmy (CT-like, PDB: 7TYI) was used as the initial template for the CTR:Cagri/CagriBB complex in the CT-like conformation by replacement of the peptide
After reconstitution the material is a solution rather than a powder, and solutions are far less stable reconstituted vials are refrigerated at 28C, kept away from light, and never frozen, since freeze-thaw cycling can precipitate peptides out of solution
World Health Organization, Geneva Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U, Shaw JE (2014) Global estimates of diabetes prevalence for 2013 and projections for 2035
Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation
Eur Heart J (2021) 42:2952