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PMID 11470726

Parallel genomic alterations of antigen and payload targets mediate polyclonal acquired clinical resistance to sacituzumab govitecan in triple-negative breast cancer

For example, Lactobacillus johnsonii reduces circulating KYN and intestinal IDO activity in rats [185], Bifidobacterium infantis increases plasma TRP and KYNA in male rats [186], and probiotic supplementation in humans lowers plasma KYN while increasing TRP levels [187]

But some pets, especially those with gastrointestinal disease, may not be able to absorb B12 effectively