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Genes involved in the pathogenesis of childhood constipation and related diseases are as following: [24] Associated Conditions Associated conditions with constipation are included: Diabetes mellitus Hypothyroidism Systemic sclerosis Parkinson's disease Depression Eating disorders Colon cancer External compression from malignant lesion Strictures: diverticular or postischemic Rectocele (if large) Postsurgical abnormalities Megacolon Anal fissure Hypercalcemia Hypokalemia Hypomagnesemia Uremia Heavy metal poisoning Myopathies Parkinson's disease Spinal cord injury or tumor Cerebrovascular disease Depression Degenerative joint disease Autonomic neuropathy Cognitive impairment Immobility Cardiac disease Gross Pathology On gross pathology, there is no finding related to constipation
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Up to a third of pregnant women with obesity are diagnosed with GDM [8], a global problem affecting one in seven pregnancies
