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Kuja-Halkola, R

Mar M, Morales A, Colell A, Garca-Ruiz C, Fernndez-Checa JC. Mitochondrial glutathione, a key survival antioxidant. Antioxid Redox Signal. 2009;11(11):2685-2700. doi:10.1089/ARS.2009.2695

The financial benefit is secondary to the biological benefit cycling prevents tolerance development that would require progressively higher doses

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Thus, tissue IGF-1 levels may be a better marker of tumor IGF-1 expression compared to serum levels, as has already been established in mammary gland branching morphogenesis [47]