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In conclusion, our study demonstrates that long-term HFD consumption results in a concomitant increase in hepatic GSSG, protein S -glutathionylation, and TNF levels

In contrast, IRP2 knockdown or treatment with the ferroptosis inhibitor Fer-1 alleviates PC-12 cell damage by downregulating p53 levels and activating the SLC7A11-ALOX12 signaling pathway (Yao et al., 2024)

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