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Under normal cellular conditions, Keap1 tethers Nrf2 in the cytoplasm (the region of the cell outside the nucleus), where it can be tagged and delivered for degradation

The nucleus accumbens, a key brain reward center, contains abundant GLP-1 receptors

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Visible/functional effects: Body-composition and recovery changes (if they occur) typically appear over weeks to months with consistent use, plus nutrition and training

Figure 2B presents these data as the cumulative number of pups per group as a function of time, which is relevant to interpreting potential impacts on the primordial reserve versus the impacts on growing follicles, with similar data showing reproductive output from individual animals in each group shown in Fig