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Preclinical studies in rodents have shown an association between GLP-1 receptor activation and thyroid C-cell changes, although a direct causal link in humans has not been established, and UK/EU SmPCs for authorised GLP-1 RAs do not list MTC or MEN2 as a formal contraindication

Seek urgent medical advice if bleeding persists beyond 10 minutes, signs of infection develop, or severe abdominal pain occurs

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Taking a double dose of Mounjaro (tirzepatide) increases drug levels in your body, which can overwhelm how it normally regulates digestion and blood sugar