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Potential to aid weight loss without drastic insulin spikes or broad hormonal effects

Cell Metabolism 2022: 10.1016/j.cmet.2022.07.002 receptor binding constants (GIP EC50 0.0643 nM, GLP-1 0.775 nM, glucagon 5.79 nM)

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It is listed as a rare adverse reaction in UK product information for both oral and injectable B12 preparations, and most people tolerate B12 supplements well even at high doses

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