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Other GLP-1 benefits besides weight loss Written by: Morgan Pennington , 10 Mar 2025 5 min read Reviewed and fact-checked: Niya Mansuri , Prescribing Pharmacist, GPhC No

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The combination of vancomycin, neomycin sulfate, metronidazole, ampicillin, and other broad-spectrum antibiotics can alleviate choline-induced atherosclerosis in mice, and the mechanism may be related to the inhibition of choline conversion to TMA, the reduction of TMAO levels, and the inhibition of macrophage foaming

Clinical trials such as SURPASS have demonstrated Tirzepatides ability to significantly reduce HbA1c levels (a marker of long-term blood glucose control) and induce substantial weight loss in patients with type 2 diabetes

Adequate hydration, fiber intake, and physical activity typically manage this effect