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Electrophysiological signals were recorded using the Axopatch 700B amplifier (Molecular Devices), low-pass filtered at 25 kHz, and analysed offline on a PC with pCLAMP programs (Molecular Devices)

367 Specifically, liraglutide, both alone and in combination with insulin, effectively suppressed the formation of osteoclasts

The model predicted rapid weight regain immediately after cessation, followed by a slowdown and a gradual approach toward a plateau in the months thereafter

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By integrating this treatment into a comprehensive weight management plan that includes customized nutrition, exercise, and ongoing follow-up, Dr