The entire process is regulated by NF-kB, a master transcription factor that controls the expression of hundreds of inflammatory genes
So if you can find another valid use for a drug, you don't have to run all the safety stuff, you don't have to do a lot of stuff, you just have to show efficacy and a few other things
Some cells maintain a massive, steady response, while others only experience a temporary spike, directly driving the differences we see in patient outcomes
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As the markers of OxS show a positive correlation with TSAb, it may indicate that these variables may be involved in the breakdown of redox balance (110)