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Tyrosine phosphorylation can be attenuated by the induction of catalase in several species (32)

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108 Unlike non-CSCs, which accumulate toxic ROS and undergo apoptosis, CSCs activate antioxidant defense systems, including superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione (GSH), and catalase (CAT), to mitigate the oxidative stress induced by cytotoxic therapy