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Both legal authorities and medical ethics counsel restraint

The biological adaptations that drive weight regain (increased ghrelin, decreased leptin, reduced metabolic rate) are strongest immediately after weight loss

That 5 to 6 percentage point difference is meaningful for many patients, and its worth factoring into a cost-per-outcome calculation rather than just a cost-per-month comparison

Hales CM, Fryar CD, Ogden CL

According to the Pituitary Society guidelines, a trial of DA tapering and withdrawal may be considered for patients who meet the following criteria [2]: (1) achievement of normal prolactin levels post-therapy