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Supplementary material The Supplementary Material for this article can be found online at: References 1 BrownleeM

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Bolam, K

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Whether its about blindness, weight loss, or side effects, no concern is too small to bring up during your consultation

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The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), traditionally recognized for their metabolic functions, also appear to influence central reward processing (14-16, 19, 20)

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A healthcare professional can assess whether dose adjustment of the medication is appropriate, review concurrent medications that may contribute to constipation, and exclude other underlying causes

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