PlexusDx offers a path to personalized GLP-1 therapy that eliminates the cost barrier while maintaining pharmaceutical quality through licensed 503A compounding pharmacies
For example, novel SBP2 truncation mutations result in abnormal thyroid function, delayed bone development, congenital myopathy, and cognitive impairment in human subjects due to deficiencies in selenoproteins, including GPx-1 (121)
trimethylamine n-oxide (TMAO), are the ones that have been linked to cardiovascular and cardio-metabolic disease (CVD, CVMD) in multiple observational studies
Similarly, fatty acid oxidation (FAO), the main pathway of fatty acid catabolism, promotes the activation of NLRP3 through NADPH oxidase 4 (NOX4)
Blundell J, Finlayson G, Axelsen M, Flint A, Gibbons C, Kvist T, et al